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Synthetic biology has advanced the design of standardized control devices that program cellular functions and metabolic activities in living organisms. Rational interconnection of these synthetic switches resulted in increasingly complex designer networks that execute input-triggered genetic instructions with precision, robustness and computational logic reminiscent of electronic circuits (...) we have designed a set of synthetic transcription–translation control devices that could be rewired in a plug-and-play manner
Programmable single-cell mammalian biocomputers
Simon Ausländer, David Ausländer, Marius Müller, Markus Wieland & Martin Fussenegger
Nature 487, 123–127 (05 July 2012) http://dx.doi.org/10.1038/nature11149
Via Complexity Digest
