Visualizing phosphodiester-bond hydrolysis by an endonuclease - Nature Structural | Bioscience News - GEG Tech top picks | Scoop.it
From www.nature.com - December 15, 2014 8:55 AM
Different catalytic steps of endonuclease I-DmoI are captured crystallographically to allow direct observation of the generation of a DNA double-strand break. A third metal ion enters the active site and has a key role in hydrolysis.