Defects in the body’s regulatory T cells cause inflammation and autoimmune disease by altering the type of bacteria living in the gut, researchers have discovered. The study suggests that replacing the missing gut bacteria, or restoring a key metabolite called inosine, could help treat children with a rare and often fatal autoimmune disease called IPEX syndrome.
A major British discovery is expected to lead to revolutionary bespoke treatments for patients with advanced cancer that could enter trials within two years.
The scientists behind the breakthrough believe they have identified the “Achilles’ heel” of cancer cells.
In a video about the findings, Cancer Research UK, described how immune cells could be marshalled to exploit this weakness.
"GEG-Tech is specialized in customized design and production of lentiviral vectors, and last November Labiotech helped to get more visitors onto their website. The campaign was a great success, leading this company to an increase in sales and to close a deal with a Big Pharma."
How does a Killer T Cell Kill its target? This new film captures the behaviour of cytotoxic T cells – the body’s ‘serial killers’ – as they hunt down and eliminate cancer cells before moving on to their next target.
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Defects in the body’s regulatory T cells cause inflammation and autoimmune disease by altering the type of bacteria living in the gut, researchers have discovered. The study suggests that replacing the missing gut bacteria, or restoring a key metabolite called inosine, could help treat children with a rare and often fatal autoimmune disease called IPEX syndrome.