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Regulatory T cells delay disease progression in Alzheimer-like pathology
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Here, the scientists analysed the impact of regulatory T cells on spontaneous disease progression in a murine model of Alzheimer’s disease. Their results suggest that regulatory T cells play a beneficial role in the pathophysiology of Alzheimer’s disease, by slowing disease progression and modulating microglial response to amyloid-β deposition. This study highlights the therapeutic potential of repurposed IL-2 for innovative immunotherapy based on modulation of regulatory T cells in Alzheimer’s disease.