Producing fuels from plants and other renewable sources requires breaking down the chemical cellulose; a major candidate to drive, or catalyze, this stubborn chemical is a ubiquitous microorganism called Clostridium thermocellum that works well in hot environments without oxygen. Researchers found that C. thermocellum uses a previously unknown mechanism to degrade cellulose, in addition to other known degradation mechanisms.
New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition. Nature, 2015; DOI: 10.1038/nature14560
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Scientists at The University of Manchester have made an important discovery that forms the basis for the development of new applications in biofuels and the sustainable manufacturing of chemicals. In this particular study, published in the journal Nature, researchers focussed on the production of alpha-olefins; a high value, industrially crucial intermediate class of hydrocarbons that are key chemical intermediates in a variety of applications, such as flexible and rigid packaging and pipes, synthetic lubricants used in heavy duty motor and gear oils, surfactants, detergents and lubricant additives.
UCR graduate researcher Cory Schwartz and professor of chemical and environmental engineering Ian Wheeldon have expanded the way yeast can be manipulated through the Clustered Regularly Interspaced Short Palindromic Repeats gene editing system (CRISPR-CAS9). With this new system, biofuels, adhesives and fragrances can be mass produced at a cheaper cost.
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Producing fuels from plants and other renewable sources requires breaking down the chemical cellulose; a major candidate to drive, or catalyze, this stubborn chemical is a ubiquitous microorganism called Clostridium thermocellum that works well in hot environments without oxygen. Researchers found that C. thermocellum uses a previously unknown mechanism to degrade cellulose, in addition to other known degradation mechanisms.