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Transmission of Diabetes Prion-Like Aggregates Triggers Disease Symptoms | GEN

Transmission of Diabetes Prion-Like Aggregates Triggers Disease Symptoms | GEN | Bioscience News - GEG Tech top picks | Scoop.it
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Scientists have shown that misfolded islet amyloid polypeptide aggregates are transmissible like prions and can trigger the development of type 2 diabetes pathogenesis in the recipient

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FDA Approves New Method to Fight Diabetes

FDA Approves New Method to Fight Diabetes | Bioscience News - GEG Tech top picks | Scoop.it

WASHINGTON (AP) — Federal regulators have approved a first-of-a-kind "artificial pancreas," a device that can help some diabetes patients manage their disease by constantly monitoring their blood sugar and delivering insulin as needed.

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Federal regulators have approved a first-of-a-kind "artificial pancreas," a device that can help some diabetes patients manage their disease by constantly monitoring their blood sugar and delivering insulin as needed.

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Google Parent and Sanofi Name Diabetes Joint Venture Onduo

Google Parent and Sanofi Name Diabetes Joint Venture Onduo | Bioscience News - GEG Tech top picks | Scoop.it
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French pharmaceutical group Sanofi is joining with Verily Life Sciences, a unit of Google parent Alphabet, to create a joint venture called Onduo to research diabetes treatments.

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Genetic test aims to improve diabetes diagnosis

Genetic test aims to improve diabetes diagnosis | Bioscience News - GEG Tech top picks | Scoop.it
metformin and glycoside - and then I was able to just continue taking those for months until I saw a consultant who then said that my diabetes had got worse. So I was actually diagnosed as type 1 then and introduced to insulin," he explained.
BigField GEG Tech's insight:

Correctly diagnosing which type of diabete a patient has is crucial, and in a small minority of cases the wrong diagnosis can be fatal. But in an age of growing obesity in the western world, diagnosis is becoming increasingly difficult for doctors.

According to diabetes expert Dr Richard Oram, from the University of Exeter Medical School, clinical diagnosis is currently based almost entirely on age at diagnosis and whether a patient is obese.

Oram's team has come up with a new, relatively inexpensive, genetic test for the disease, which he thinks will help doctors.

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This Common Medicine Might Help Fight Leukemia

This Common Medicine Might Help Fight Leukemia | Bioscience News - GEG Tech top picks | Scoop.it
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Common diabetes drugs might help eradicate drug-resistant cancer cells in a certain form of leukemia when added to standard treatment, a small new study suggests.


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Temporary Tattoo Offers Needle-Free Way to Monitor Glucose Levels

Temporary Tattoo Offers Needle-Free Way to Monitor Glucose Levels | Bioscience News - GEG Tech top picks | Scoop.it

Nanoengineers at the University of California, San Diego have tested a temporary tattoo that both extracts and measures the level of glucose in the fluid in between skin cells. This first-ever example of the flexible, easy-to-wear device could be a promising step forward in noninvasive glucose testing for patients with diabetes.


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Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis

Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis | Bioscience News - GEG Tech top picks | Scoop.it
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This study points out that the GAD65 protein unpredictable behavior much like Dr. Jekyll and Mr. Hyde. Indeed this protein is essential to the synthesis of some neurotransmitters but could be also presents in the pancreas where it could induce diabete of type 1.

 

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Diabetes advance: Cells produce insulin upon artemisinin treatment

Diabetes advance: Cells produce insulin upon artemisinin treatment | Bioscience News - GEG Tech top picks | Scoop.it
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FDA-approved artemisinins, which have been used for decades to treat malaria, transform glucagon-producing alpha cells in the pancreas into insulin producing cells, researchers report.

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SNAILS' SPEEDY INSULIN
BIO-INSPIRED INSULIN MAY ACT THREE TIMES FASTER THAN CURRENT PRODUCTS

SNAILS' SPEEDY INSULIN<br/>BIO-INSPIRED INSULIN MAY ACT THREE TIMES FASTER THAN CURRENT PRODUCTS | Bioscience News - GEG Tech top picks | Scoop.it
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University of Utah researchers have found that the structure of an insulin molecule produced by predatory cone snails may be an improvement over current fast-acting therapeutic insulin. The finding suggests that the cone snail insulin, produced by the snails to stun their prey, could begin working in as few as five minutes, compared with 15 minutes for the fastest-acting insulin currently available. Biologist Helena Safavi, co-author on a paper describing the cone snail insulin published September 12 in Nature Structural & Molecular Biology, says that studying complex venom cocktails can open doors to new drug discoveries.

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Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance - Cancer Cell

Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance - Cancer Cell | Bioscience News - GEG Tech top picks | Scoop.it

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French researchers have modified a molecule used in the treatment of diabetes to destroy melanoma. This strategy could be used for patients resistant to current therapies.

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Detect Diabetes in Seconds with Saliva Sample and a Smart Phone

Detect Diabetes in Seconds with Saliva Sample and a Smart Phone | Bioscience News - GEG Tech top picks | Scoop.it
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Diabetes often referred to by doctors as diabetes mellitus is considered to be one of the leading causes of death. Having this kind of disease doubles your chance of acquiring heart attack. Knowledge about the disease will prevent someone from getting it or it can lessen the risks for diabetes complications. There has been several ways in detecting if someone suffers from it.


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ROR Inverse Agonist Suppresses Insulitis and Prevents Hyperglycemia in a Mouse Model of Type 1 Diabetes

ROR Inverse Agonist Suppresses Insulitis and Prevents Hyperglycemia in a Mouse Model of Type 1 Diabetes | Bioscience News - GEG Tech top picks | Scoop.it
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To investigate the roles and therapeutic potential for targeting the RORs in type 1 diabetes, the scientists administered SR1001, a selective RORα/γ inverse agonist, to non-obese diabetic (NOD) mice. SR1001 significantly reduced diabetes incidence and insulitis in treated mice. Furthermore, SR1001 reduced pro-inflammatory cytokine expression, particularly TH17-mediated cytokines, reduced autoantibody production, and increased the frequency of CD4+Foxp3+ T regulatory cells.


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Genetic code for diabetes in Greenland broken by scientists

Genetic code for diabetes in Greenland broken by scientists | Bioscience News - GEG Tech top picks | Scoop.it
New ground-breaking genetics research explains the high incidence of type 2 diabetes in the Greenlandic population, based on blood samples from 5,000 people or approximately 10% of the population. "Several epidemiological studies have looked at the health implications of the transition from life as sealers and hunters in small isolated communities to a modern lifestyle with appreciable dietary changes. Perhaps the gene variant which has been identified can be interpreted as a sign of natural selection as the traditional Greenlandic diet consisted primarily of protein and fat from sea animals," one researcher said.
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Compact breath sniffer could warn of diabetes

Compact breath sniffer could warn of diabetes | Bioscience News - GEG Tech top picks | Scoop.it
If you're worried about being out of shape, or suspect you might have a disease like diabetes, just breathe into this Toshiba tube.
BigField GEG Tech's insight:

Toshiba's New Breathalyzer Diagnoses Diseases. Interesting!

 

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