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How artificial intelligence is poised to reshape medicine

How artificial intelligence is poised to reshape medicine | Bioscience News - GEG Tech top picks | Scoop.it
In a recent review published in the journal of Nature Medicine, researchers discussed the results of a two-year weekly effort to track and communicate significant developments in medical (artificial intelligence) AI. They included prospective studies as well as developments in medical image analysis that have narrowed the gap between research and implementation.
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In a recent review published in the journal Nature Medicine, scientists discussed the results of a two-year weekly effort to track and communicate significant developments in medical AI. In particular, AI has been a game-changer in the crucial task of protein folding, which involves predicting the 3D structure of a protein from its chemical sequence. Improvements in protein structure prediction can reveal mechanistic information about a variety of events, including drug-protein interactions and mutation effects. With AI, non-invasive cancer screening, prognosis, and tumor origin identification are now possible. Moreover, deep learning has improved CRISPR-based gene editing by helping predict guide RNA activity and identifying anti-CRISPR protein families. According to one study, BioBERT, a model trained on a large corpus of medical literature, outperformed previous peers on natural language tasks such as answering biological questions.  

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Drugs from nature: big effects of multiple compounds in small amounts

Drugs from nature: big effects of multiple compounds in small amounts | Bioscience News - GEG Tech top picks | Scoop.it
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Nature often produces a whole weaponry of active ingredients to ensure it is well prepared for any scenario that might occur. The research group led by Professor Helge Bode has now discovered a whole class of new peptides with which bacteria are able to kill insect larvae.

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Drug’s Toxicity Caused Clinical-Trial Death, Panel Says

Drug’s Toxicity Caused Clinical-Trial Death, Panel Says | Bioscience News - GEG Tech top picks | Scoop.it

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In a report published Tuesday by the French Agency for the Safety of Health Products, experts said that the incident “seemed clearly linked” to the “molecule” being tested, rather than possible mistakes in how the drug was administered or dosage.

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How Pfizer Set the Cost of Its New Drug at $9,850 a Month

How Pfizer Set the Cost of Its New Drug at $9,850 a Month | Bioscience News - GEG Tech top picks | Scoop.it
With U.S. Drug Costs in the Cross Hairs, a Look at How Pfizer Set a Breast-Cancer Medicine’s Price Shows an Elaborate Process of Testing the Market
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Three years of market research—a stretch that started almost as soon as the new treatment showed promise in the laboratory—was suddenly in doubt. After carefully calibrating the price to be close to rivals and to keep doctors and insurers happy, Pfizer was left wondering if its list price of $9,850 a month for the pills was too low.

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Alcoholism drug found to bring dormant HIV into the open to be treated

Alcoholism drug found to bring dormant HIV into the open to be treated | Bioscience News - GEG Tech top picks | Scoop.it
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A drug used to treat alcoholism can bring dormant HIV out of cells to be killed by antiretroviral therapy AIDS drugs.


www.geg-tech.com/Vectors

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This Common Medicine Might Help Fight Leukemia

This Common Medicine Might Help Fight Leukemia | Bioscience News - GEG Tech top picks | Scoop.it
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Common diabetes drugs might help eradicate drug-resistant cancer cells in a certain form of leukemia when added to standard treatment, a small new study suggests.


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Drugs that target 'epigenetic scars' may reverse drug addiction | Genetic Literacy Project

Drugs that target 'epigenetic scars' may reverse drug addiction | Genetic Literacy Project | Bioscience News - GEG Tech top picks | Scoop.it
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Research is mounting that not only does epigenetics play an important role in drug addiction, it may also provide a way to reverse it.

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New antibody-based drug for multiple sclerosis

New antibody-based drug for multiple sclerosis | Bioscience News - GEG Tech top picks | Scoop.it

http://brain.oxfordjournals.org/content/early/2016/07/19/brain.aww172

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Inserm Unit U919, directed by Prof. Denis Vivien ("Serine Proteases and Physiopathology of the Neurovascular Unit") has developed an antibody with potential therapeutic effects against multiple sclerosis. The study, directed by Fabian Docagne and published in Brain, paves the way for a new strategy to control the disease.

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Anti-inflammatory drugs can fix some signs of depression in mice

Anti-inflammatory drugs can fix some signs of depression in mice | Bioscience News - GEG Tech top picks | Scoop.it
The idea that inflammation in the brain could be implicated in depression is in vogue, but mouse drug trials suggest it's only part of the story
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Could an inflamed brain be behind mental health disorders such as depression and schizophrenia? It’s one of the hottest ideas in psychiatry, but now it seems it’s only part of the picture: blocking inflammation in mice only relieved some of the signs of depression.

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Promising drug combination for advanced prostate cancer

Promising drug combination for advanced prostate cancer | Bioscience News - GEG Tech top picks | Scoop.it
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A new drug combination may be effective in treating men with metastatic prostate cancer. Preliminary results of this new approach are encouraging and have led to an ongoing international study being conducted in 196 hospitals worldwide.


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Robotic Fish May Swim Inside Us One Day

Robotic Fish May Swim Inside Us One Day | Bioscience News - GEG Tech top picks | Scoop.it
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Scientists use innovative 3-D printing technology to create self-powered robots that could deliver drugs or remove toxins. Researchers at the University of California, San Diego, have built tiny fishlike robots that could eventually perform a variety of important tasks, from delivering a highly targeted drug payload inside a human body to detecting or even removing toxins from a liquid environment.


www.geg-tech.com/Vectors

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