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Nerve cells from the brain invade prostate tumours - Nature

Nerve cells from the brain invade prostate tumours - Nature | Bioscience News - GEG Tech top picks | Scoop.it
The source found of newly formed nerve cells in prostate cancer.
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Prostate cancer contains nerve cells that are linked to disease progression, but their source was unknown. A mouse study reveals that cells from the brain invade prostate tumours and give rise to this nerve-cell population.

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Test Tube Artificial Neural Network Recognizes "Molecular Handwriting" | Caltech

Test Tube Artificial Neural Network Recognizes "Molecular Handwriting" | Caltech | Bioscience News - GEG Tech top picks | Scoop.it
Caltech scientists have developed an artificial neural network out of DNA that can recognize highly complex and noisy molecular information.
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Researchers at Caltech have developed an artificial neural network made out of DNA that can solve a classic machine learning problem: correctly identifying handwritten numbers. The work is a significant step in demonstrating the capacity to program artificial intelligence into synthetic biomolecular circuits.

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A giant neuron found wrapped around entire mouse brain

A giant neuron found wrapped around entire mouse brain | Bioscience News - GEG Tech top picks | Scoop.it
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3D reconstructions show a 'crown of thorns' shape stemming from a region linked to consciousness.

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First direct evidence for synaptic plasticity in fruit fly brain

First direct evidence for synaptic plasticity in fruit fly brain | Bioscience News - GEG Tech top picks | Scoop.it
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Scientists have resolved a decades-long debate about how the brain is modified when an animal learns. Using newly developed tools for manipulating specific populations of neurons, the researchers have for the first time observed direct evidence of synaptic plasticity -- changes in the strength of connections between neurons -- in the fruit fly brain while flies are learning.


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3D brain map reveals connections between cells in nano-scale

3D brain map reveals connections between cells in nano-scale | Bioscience News - GEG Tech top picks | Scoop.it

http://www.cell.com/cell/abstract/S0092-8674(15)00824-7?_returnURL=http%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0092867415008247%3Fshowall%3Dtrue


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Scientists have created an unprecedented high-resolution map of the brain that reveals structures as small as those found in individual nerve cells.

They hope images will enable study of abnormal connections betdepressionween cells present in neurological disorders such as schizophrenia and depression.


www.geg-tech.com/Vectors


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Schwann cells transduced with a lentiviral vector encoding Fgf-2 promote motor neuron regeneration following sciatic nerve injury - 2014 - Glia

Schwann cells transduced with a lentiviral vector encoding Fgf-2 promote motor neuron regeneration following sciatic nerve injury - 2014 - Glia | Bioscience News - GEG Tech top picks | Scoop.it
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Authers investigate the in vivo effect of FGF-2 overexpression on axonal regeneration after nerve injury. They transduced Schwann cells with LV-FGF2 which were grafted to repair the resected rat sciatic nerve. Electrophysiological tests conducted for up to 2 months after injury revealed accelerated and more marked reinnervation of hindlimb muscles in the animals treated with LV-FGF2, with an increase in the number of motor and sensory neurons that reached the distal tibial nerve at the end of follow-up.

 

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BigField GEG Tech's curator insight, July 9, 2014 10:57 AM

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Authers investigate the in vivo effect of FGF-2 overexpression on axonal regeneration after nerve injury. They transduced Schwann cells with LV-FGF2 which were grafted to repair the resected rat sciatic nerve. Electrophysiological tests conducted for up to 2 months after injury revealed accelerated and more marked reinnervation of hindlimb muscles in the animals treated with LV-FGF2, with an increase in the number of motor and sensory neurons that reached the distal tibial nerve at the end of follow-up.

 

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Penn Researchers Discover the Source of New Neurons in Brain Hippocampus – PR News

A Common Embryonic Origin of Stem Cells Drives Developmental and Adult Neurogenesis
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Researchers from the Perelman School of Medicine at the University of Pennsylvania have shown, in mice, that one type of stem cell that makes adult neurons is the source of this lifetime stock of new cells in the hippocampus.

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Learning through ferroelectric domain dynamics in solid-state synapses

Learning through ferroelectric domain dynamics in solid-state synapses | Bioscience News - GEG Tech top picks | Scoop.it
Accurate modelling of memristor dynamics is essential for the development of autonomous learning in artificial neural networks.
BigField GEG Tech's insight:

In promising solid-state synapses called memristors, conductance can be finely tuned by voltage pulses and set to evolve according to a biological learning rule called spike-timing-dependent plasticity (STDP). Future neuromorphic architectures will comprise billions of such nanosynapses, which require a clear understanding of the physical mechanisms responsible for plasticity. Here the authors report on synapses based on ferroelectric tunnel junctions and show that STDP can be harnessed from inhomogeneous polarization switching.

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Translation dynamics of single mRNAs in live cells and neurons

Translation dynamics of single mRNAs in live cells and neurons | Bioscience News - GEG Tech top picks | Scoop.it
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The Einstein scientists observed the translation of single mRNA molecules in two types of cells: human cancer (osteosarcoma) cells and mouse neurons. The scientists made a surprising finding in neurons, where mRNA translation into protein was found to occur in “bursts”—a phenomenon never before possible to observe. 

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Karolinska Institutet: Artificial neuron mimics function of human cells

Karolinska Institutet: Artificial neuron mimics function of human cells | Bioscience News - GEG Tech top picks | Scoop.it
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Scientists at Sweden’s Karolinska Institutet have managed to build a fully functional neuron by using organic bioelectronics. This artificial neuron contain no ‘living’ parts, but is capable of mimicking the function of a human nerve cell and communicate in the same way as our own neurons do.


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In Vivo Measurement of Cell-Type-Specific Synaptic Connectivity and Synaptic Transmission in Layer 2/3 Mouse Barrel Cortex

In Vivo Measurement of Cell-Type-Specific Synaptic Connectivity and Synaptic Transmission in Layer 2/3 Mouse Barrel Cortex | Bioscience News - GEG Tech top picks | Scoop.it
BigField GEG Tech's insight:

Scientists have used a cutting-edge method to stimulate neurons with light. They have successfully recorded synaptic transmission between neurons in a live animal for the first time.


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