The source found of newly formed nerve cells in prostate cancer.
BigField GEG Tech's insight:
Prostate cancer contains nerve cells that are linked to disease progression, but their source was unknown. A mouse study reveals that cells from the brain invade prostate tumours and give rise to this nerve-cell population.
Caltech scientists have developed an artificial neural network out of DNA that can recognize highly complex and noisy molecular information.
BigField GEG Tech's insight:
Researchers at Caltech have developed an artificial neural network made out of DNA that can solve a classic machine learning problem: correctly identifying handwritten numbers. The work is a significant step in demonstrating the capacity to program artificial intelligence into synthetic biomolecular circuits.
Scientists have resolved a decades-long debate about how the brain is modified when an animal learns. Using newly developed tools for manipulating specific populations of neurons, the researchers have for the first time observed direct evidence of synaptic plasticity -- changes in the strength of connections between neurons -- in the fruit fly brain while flies are learning.
Scientists have created an unprecedented high-resolution map of the brain that reveals structures as small as those found in individual nerve cells.
They hope images will enable study of abnormal connections betdepressionween cells present in neurological disorders such as schizophrenia and depression.
Authers investigate the in vivo effect of FGF-2 overexpression on axonal regeneration after nerve injury. They transduced Schwann cells with LV-FGF2 which were grafted to repair the resected rat sciatic nerve. Electrophysiological tests conducted for up to 2 months after injury revealed accelerated and more marked reinnervation of hindlimb muscles in the animals treated with LV-FGF2, with an increase in the number of motor and sensory neurons that reached the distal tibial nerve at the end of follow-up.
Authers investigate the in vivo effect of FGF-2 overexpression on axonal regeneration after nerve injury. They transduced Schwann cells with LV-FGF2 which were grafted to repair the resected rat sciatic nerve. Electrophysiological tests conducted for up to 2 months after injury revealed accelerated and more marked reinnervation of hindlimb muscles in the animals treated with LV-FGF2, with an increase in the number of motor and sensory neurons that reached the distal tibial nerve at the end of follow-up.
Researchers from the Perelman School of Medicine at the University of Pennsylvania have shown, in mice, that one type of stem cell that makes adult neurons is the source of this lifetime stock of new cells in the hippocampus.
Accurate modelling of memristor dynamics is essential for the development of autonomous learning in artificial neural networks.
BigField GEG Tech's insight:
In promising solid-state synapses called memristors, conductance can be finely tuned by voltage pulses and set to evolve according to a biological learning rule called spike-timing-dependent plasticity (STDP). Future neuromorphic architectures will comprise billions of such nanosynapses, which require a clear understanding of the physical mechanisms responsible for plasticity. Here the authors report on synapses based on ferroelectric tunnel junctions and show that STDP can be harnessed from inhomogeneous polarization switching.
The Einstein scientists observed the translation of single mRNA molecules in two types of cells: human cancer (osteosarcoma) cells and mouse neurons. The scientists made a surprising finding in neurons, where mRNA translation into protein was found to occur in “bursts”—a phenomenon never before possible to observe.
Scientists at Sweden’s Karolinska Institutet have managed to build a fully functional neuron by using organic bioelectronics. This artificial neuron contain no ‘living’ parts, but is capable of mimicking the function of a human nerve cell and communicate in the same way as our own neurons do.
Scientists have used a cutting-edge method to stimulate neurons with light. They have successfully recorded synaptic transmission between neurons in a live animal for the first time.
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Prostate cancer contains nerve cells that are linked to disease progression, but their source was unknown. A mouse study reveals that cells from the brain invade prostate tumours and give rise to this nerve-cell population.