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Bioscience News - GEG Tech top picks
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Star-shaped engineered peptide nanoparticles are effective at killing a variety of multidrug-resistant Gram-negative pathogens in vivo with low host toxicity and resistance.
BigField GEG Tech's insight:
Here, the authors show that a class of antimicrobial agents, termed ‘structurally nanoengineered antimicrobial peptide polymers’ (SNAPPs) exhibit sub-μM activity against all Gram-negative bacteria tested, including ESKAPE and colistin-resistant and MDR (CMDR) pathogens, while demonstrating low toxicity. 
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BigField GEG Tech's insight:
Researchers at UT Southwestern Medical Center have developed a strategy to overcome a key defense that drug-resistant bacteria use to fend off antibiotic attack.
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BigField GEG Tech's insight:
The researchers, who published their findings in this week's edition of theJournal of Antibiotics, say their latest discovery could permit chemists and others to understand how mixtures of potential antibiotics from microorganisms work without first purifying them. It builds on their development two years ago of a new way to rapidly identify new compounds capable of killing bacteria.
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BigField GEG Tech's insight:
The growing antibiotic resistance of the bacteria gives a new sense of urgency to the problem as world leaders met at the UN for the first summit on superbugs.
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Drug resistance is no longer a matter of health. It could have massive implications for the world's economy and food supply.
BigField GEG Tech's insight:
Historical. A possible turning point. These are the words health researchers are using to describe a declaration passed Wednesday by the U.N. General Assembly aiming to slow down the spread of superbugs — bacteria that have become resistant to antibiotics.
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BigField GEG Tech's insight:
In a creative stroke inspired by Hollywood wizardry, scientists have designed a simple way to observe how bacteria move as they become impervious to drugs
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BigField GEG Tech's insight:
Researchers at South China Agricultural University, lead by Liu Jianhua, have discovered a gene in China, called MCR-1, which makes bacteria resistant against polymyxins. Chinese pigs are a few of the biggest consumers of the drug colistin, a kind of polymyxin, which is used to fatten them up.
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Six European countries, the UK’s Wellcome Trust and South Africa have committed €56.5M to the GARDP to work on breaking antibiotic resistance.