OPN-305 from Opsona Therapeutics is a potent inhibitor of TLR mediated pro-inflammatory cytokine production
Via Krishan Maggon
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Research also suggests that the scope for TLR antagonists such as OPN-305 extends to other important inflammatory diseases including diabetes, lupus and Alzheimer's disease.
Opsona’s OPN-305 patent has recently been granted in a number of jurisdictions includingEurope (EP2451842B2) and the USA (US8,734,794B2). Opsona has several other patents surrounding OPN-305, including compositions, methods and epitope binding domains.