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Listeria monocytogenes is a gram-positive bacteria and human pathogen widely used in cancer immunotherapy because of its capacity to induce a specific cytotoxic T cell response in tumours.
Via Krishan Maggon
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Rescooped by Gilbert C FAURE from Cancer Vaccines Collection |
Scoop.it!
Via Krishan Maggon
These results support the use of low doses of pathogenic Listeri as safe melanoma therapeutic vaccines that do not require antibiotics for bacterial removal.
Citation: Bronchalo-Vicente L, Rodriguez-Del Rio E, Freire J, Calderon-Gonzalez R, Frande-Cabanes E, et al. (2015) A Novel Therapy for Melanoma Developed in Mice: Transformation of Melanoma into Dendritic Cells with Listeria monocytogenes. PLoS ONE 10(3): e0117923. doi:10.1371/journal.pone.0117923