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Researchers were surprised to find that people with Type 2 diabetes who lost a lot of weight didn't lower their risk of heart attacks or strokes. They did have better control of their blood sugar and saw other health benefits. 
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Break your better-eating resolution into 12 manageable parts and implement one each month.
Ray and Terry's 's insight:
Also in this article, 25 recipes under 500 calories.
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Approximately 68 percent of U.S. adults are overweight or obese, according to the National Cancer Institute, which puts them at greater risk for developing cancer, cardiovascular disease, diabetes and a host of other chronic illnesses.
But an international team of scientists led by Virginia Commonwealth University Massey Cancer Center researcher Andrew Larner, M.D., Ph.D., has successfully reversed obesity in mice by manipulating the production of an enzyme known as tyrosine-protein kinase-2 (Tyk2). In their experiments, the scientists discovered that Tyk2 helps regulate obesity in mice and humans through the differentiation of a type of fat tissue known as brown adipose tissue (BAT).
Ray and Terry's 's insight:
This discovery may lead to methods to treat obesity by modulating levels of the enzyme. If successful, not only would obesity rates decrease, but healthy life span would increase.
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Just walk away from the buffet table before they start telling you that you’d be perfect as Santa Claus.
Ray and Terry's 's insight:
How can you survive the holiday eating season without packing on pounds? Be prepared and consider the choices you make carefully. In the long run, you won't have to fight to take off the extra weight and that just might make it worth skipping a cookie and a glass of eggnog.
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Don’t blame the turkey. You’ll most likely find the calorie culprits right next to it: the sides. Many popular Thanksgiving cooking techniques include breading, frying or smothering with high-fat sauces that significantly increase calories and saturated fat. And we often miss out on the opportunity to incorporate beneficial foods such as whole grains and vegetables.
This year, start by eating a healthful breakfast and sensible snacks throughout the day to avoid overeating during dinner. And when you do get to the big event, remember that Thanksgiving’s main star, the turkey, can be enjoyed healthfully.
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Apple's Amazing Polyphenols In the past five years, no area of apple research has been more dynamic than the area of apple polyphenols. The balance of these phytonutrients in apples is far more unique than many researchers previously suspected.
In terms of flavonols, quercetin is the primary phytonutrient found in apples, and it's far more concentrated in the skin than in the pulp. Kaempferol and myricetin are also important apple flavonols.
Chlorogenic acid is apple's primary phenolic acid, and it's found throughout the pulp and also in the skin. Chlorogenic acid is a metabolism boosting compound also found in the popular new green coffee bean extracts. It help supress appetite and stimulate weight loss.
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Vaccines and antibiotics may someday join caloric restriction or bariatric surgery as a way to regulate weight gain, according to a new study focused on the interactions between diet, the bacteria that live in the bowel, and the immune system.
Researchers examined the complicated relationship between the immune system, gut bacteria, digestion and obesity. They showed how weight gain requires not just caloric overload but also a delicate, adjustable -- and transmissible -- interplay between intestinal microbes and the immune response.
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A prototype bathroom scale not only measures the user's weight, but also performs an electrocardiogram on them.
People who need monitoring for heart conditions may not have to go to the hospital as often for testing, if this new design can be produced for home use.
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The existence of two different types of fat – or adipose tissue – in mammals has long been known: white fat, which stores calories and in excess results in obesity, and brown fat, which burns calories to generate energy and heat. Now scientists at the Dana-Farber Cancer Institute have confirmed the existence of a third, genetically distinct type of fat called “beige fat,” which they say is a potential therapeutic target for treating obesity.
A 2008 paper out of the Dana-Farber lab of Bruce Spiegelman, PhD, had proposed the existence of a third type of fat cell, and now Spiegelman and his team have become the first to isolate them and determine beige fat’s unique genetic profile. They found that beige fat shares much in common with brown fat. Both have the ability to burn large amounts of calories as they both contain energy-burning organelles called mitochondria, which contain iron and are responsible for the cells’ brown and beige hues.
"The therapeutic potential of both kinds of brown fat cells is clear," the authors say in their study, "as genetic manipulations in mice that create more brown or beige fat have strong anti-obesity and anti-diabetic actions."
However...
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A team of Swiss researchers has discovered that raising the levels of the hormone erythropoietin (Epo) in the brains of mice resulted in the rodents being more motivated to exercise.
The discovery provides the possibility of developing a pill that can motivate people to want to exercise.
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Wondering if a high-fat, heart healthy Mediterranean diet is better than the low fat heart healthy diets?
Kardea Nutrition has written a report that will help you find an answer that works for you. Learn the 5 Rules for Eating Healthy Oils and the 6 Steps for Keeping Healthy Oils Healthy (pdf)
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Disruption in circadian rhythms can lead to higher instances of weight gain and diabetes.
Humans have not evolved to efficiently work the night shift.
Ray and Terry's 's comment,
May 22, 2012 7:37 AM
Disruption of the ‘biological clock’ may cause downslide to early death.
http://www.kurzweilai.net/disruption-of-biological-clocks-causes-neurodegeneration-early-death
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Misconceptions about technique, tools and timing can sabotage efforts to get in shape.
How clear are you about the facts vs. myths of exercise? Test yourself with this mini quiz:
-Should you lift weights? -Can you target fat spots? -Is the scale top priority? ...
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Researchers from the University of Bonn have treated mice with Viagra and discovered that the drug converts white fat cells (those unwanted denizens of the belly and similar swollen regions) into beige fat cells. Instead of storing excess energy, these recently discovered beige fat cells burn the energy from ingested food and convert it to heat. Viagra also appears (at least in mice) to decrease the risk of other complications caused by obesity.
Austin Newby's curator insight,
December 10, 2015 3:52 PM
1. The author has facts from scientific studies to prove that the case that 'Viagra could prove useful in the fight against obesity', The author has proven their case very effectively 2. This article explains that a drug may help in the obesity crisis. 3. It is a very interesting article with a rather odd topic.
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With health authorities saying the world is facing an obesity epidemic and with a recent major study finding that – for the first time – more people now die from obesity-related illnesses like heart attacks and strokes than malnutrition, scientists have been tackling the fat problem.
Recent approaches to this problem include looking at ways to slow down the biological clock and converting calorie-storing white fat cells into heat-generating brown fat cells. Now, a new study has found that linking two hormones into a single molecule could lead to improved treatments for medical conditions such as obesity.
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Instead of solid fats such as butter and shortening, go for vegetable oils such as canola oil for less saturated and trans fat. Even better, unsweetened applesauce can replace half the oil in your recipe to help cut down on overall fat. The applesauce also adds natural sweetness and fiber. Canned pumpkin or sweet potato puree can also be used as a substitute for these solid fats while also offering health benefits from vitamins A and C.
Ray and Terry's 's insight:
If you have time to bake this season, here are some tips to make it more forgiving to eat the results.
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Daily probiotic yogurt consumption may improve energy metabolism and reduce body fat levels by up to 4%, say results of a placebo-controlled, double-blind cross-over clinical trial in Canada.
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What's your typical pick for a morning meal? Does it involve a cup of coffee with toast and fruit?
You are in good company if you eat breakfast. Those that do tend to be leaner and healthier. Besides, it is a good time to get extra fruits or vegetables, plus whole grains in your diet.
There are benefits to blood sugar, heart health, cholesterol, weight. Don't skip breakfast if you are interested in optimal health.
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NEW YORK (Reuters Health) - The short-term benefits of weight loss surgery are well known in severely obese people, but a new study finds that improvements in diabetes and blood pressure may hold up for years after the procedures.
At six-year patient follow-ups, three quarters of people who'd undergone gastric bypass surgery had lost at least 20 percent of their pre-surgery weight and kept it off, researchers found.
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Earlier this year, a team from UC San Francisco reported on the discovery that a class of commonly prescribed type-2 diabetes drugs, called TZDs (thiazolidinediones, such as Actos and Avandia), promoted the conversion of energy-storing white fat cells into energy-burning brown fat cells. Now researchers at Columbia University Medical Center (CUMC) have identified the mechanism that causes this change to take place, potentially leading to new treatments for obesity and type-2 diabetes.
While it was known that TZDs have the ability to change white fat cells to brown fat cells by activating a cell receptor called peroxisome proliferator-activated receptor–gamma (ppar-gamma), the exact mechanism behind this transformation was unclear. Because TZDs have numerous adverse side effects,
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There is a glut of health-related smartphone apps. But how many are of any real use? And what are some of the benefits of using one of these apps?
Beyond calorie tracking, there are actually quite a few apps out there that can help push you towards your optimal health. You can check symptoms, maintain healthy weight, monitor blood pressure, track supplements, and even make sure you brush your teeth properly.
Check out these top 10 suggestions (most are free) health apps from one source.
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The striking results of a small clinical trial support the Atkins approach to weight control.
That diet plan advocates a diet very low in carbohydrates (sugars and starches), with ample proportions of fat and protein.
Unfortunately, Dr. Atkins failed to discriminate among types of fat, which have very different metabolic effects.
There’s little doubt that diets too high in omega-6 and saturated fats relative to omega-3 fats – such as the standard American diet – produce unhealthful effects.
Two cautions about the new study are in order
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Reuters) - Extra weight may not be good for your health in general, but heavy men appear more likely to survive a particular form of immune system cancer, according to a U.S. study
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Most of us can be described as sedentary. Even if you go to the gym first thing in the morning, you might not be moving enough.
Denise Austin reminds us “On the hour, do a minute.” Move, stretch, walk, stand up… do whatever you can to keep your body active.
The biggest challenge? Getting and STAYING motivated! Make sure to keep moving, even if the weather gets hot. Make a resolution to take advantage of more outdoor activities this summer.
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Researchers from Purdue University in Indiana are testing a compound found in red wine that has the ability to block the processes of fat cell development. The research into the compound known as piceatannol may lead towards finding a simple method to combat obesity.
Piceatannol results from the conversion of resveratrol – a compound found in red wine, grapes and peanuts that is also thought to combat cancer, heart disease and neurodegenerative diseases. When resveratrol is converted into the piceatannol
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