Longevity science

Metoprolol had already been identified by me as a life extending drug based on two human RCTs which reported mortality reductions in hypertensives that exceeded the standard mortality rate, as well as the control groups. PMID: 3293400, PMID: 1682683. 

There is no indication that these hypertensives should have mortality rates better than the general population, therefore the bettering of the standard mortality rates makes these drugs anti-aging.

THE BENEFIT IS ABOUT 45% EQUALING BETTER THAN A SIX YEAR LIFE EXTENSION FOR HUMANS

Gerontologists and demographers have argued about this for a long time, with the balance of opinion heavily influenced by the changes seen in the wealthiest nations’ “survival curves” — graphs showing, broadly speaking, the proportion of an initial population that survived to a given age.

How do they do it?

There are two types of worm that can regenerate their cells indefinitely, leading researchers to question—is this a key to immortality?

The latest in the fight against ever dying is a gene therapy that gives mice a healthy dose of telomerase, the enzyme that keeps our chromosomes – and thus our cells and bodies – “young.”

The therapy extended the lifespans of mice by 24 percent and, at least so far, the therapy appears to be completely safe...

"People worldwide are living three years longer than expected on average, pushing up the costs of aging by 50 percent, and governments and pension funds are ill prepared, the International Monetary Fund said.

Already the cost of caring for aging baby boomers is beginning to strain government budgets, particularly in advanced economies where by 2050 the elderly will match the numbers of workers almost one for one. The IMF study shows that the problem is global and that longevity is a bigger risk than thought.”

A few weeks ago, PBS NewsHour ran a 10-minute piece with Kurzweil titled “As Humans and Computers Merge…Immortality?” from correspondent Paul Solman for his economics-focused Making Sen$e of Financial News.

Solman probes Kurzweil for some insights about where technology is headed in the coming decades, covering topics like artificial intelligence, extending lifespans through supplementation, and digital resurrection of the deceased as avatars.

Although people are living longer as a group, the maximum lifespan seems to be fixed at 114. Why?

There are a number of potential explanations, but we may find that today’s predictions and reasons are completely irrelevant in tomorrow's world.