Your new post is loading...
Roland D. Kersten at Moore's lab describes natural product peptidogenomics (NPP), a new MS-guided genome-mining method that connects the chemotypes of peptide natural products to their biosynthetic gene clusters by iteratively matching de novo tandem MS (MS(n)) structures to genomics-based structures following biosynthetic logic.
Nature Chemical Biology7,794–802(2011) http://dx.doi.org/10.1038/nchembio.684
Moore's lab http://moorelab.ucsd.edu/
