Dysregulation of the complement system is evident in many CNS diseases but mechanisms regulating complement activation in the CNS remain unclear.
Via Krishan Maggon
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Citation: Aeinehband S, Lindblom RPF, Al Nimer F, Vijayaraghavan S, Sandholm K, et al. (2015) Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis. PLoS ONE 10(4): e0122048. doi:10.1371/journal.pone.0122048