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The CCR5 protein is a G protein-coupled receptor which functions as a chemokine receptor and predominantly expressed on immune T cells, macrophages, dendritic cells and microglia.
CCR5-Δ32 is a deletion mutation found in about 10% of people of Northern Europe (at least one copy) and in those of Northern European descent.
Individuals with the Δ32 allele of CCR5 are healthy, suggesting that CCR5 is largely dispensable.
The CCR5-Δ32 mutation appears to protect against HIV and smallpox (Variola virus).
(source: Wikipedia, modified)
