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Virus World provides a daily blog of the latest news in the Virology field and the COVID-19 pandemic. News on new antiviral drugs, vaccines, diagnostic tests, viral outbreaks, novel viruses and milestone discoveries are curated by expert virologists. Highlighted news include trending and most cited scientific articles in these fields with links to the original publications. Stay up-to-date with the most exciting discoveries in the virus world and the last therapies for COVID-19 without spending hours browsing news and scientific publications. Additional comments by experts on the topics are available in Linkedin (https://www.linkedin.com/in/juanlama/detail/recent-activity/)
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New Predictions by IHME Estimate Over 208,000 COVID-19 U.S. Deaths by November

New Predictions by IHME Estimate Over 208,000 COVID-19 U.S. Deaths by November | Virus World | Scoop.it

Updated  projections (July 7) by the Institute of Health Metrics and Evaluation (IHME), now estimate over 208,000 total deaths in the United States by November first. These new numbers estimate 75,000 additional deaths will occur in the following 4 months. The model predicts that up to 40,000 deaths can be avoided by implementing universal wearing of face masks in the U.S. The model forecasts 600-700 daily deaths  in the U.S. through the summer, later increasing as we enter into the flu season.

 

By comparison, under easing mandates, near 1300 average daily deaths  are predicted by November in the U.S. The model also estimates significant burden of disease in Brazil,  with 176,000 cumulative  deaths by the first of November.

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COVID-19  Predictions Based on Social, Economic, Demographic Factors and Shutdown Days

COVID-19  Predictions Based on Social, Economic, Demographic Factors and Shutdown Days | Virus World | Scoop.it

The spread of the COVID-19 virus is highly variable among U.S. counties. Seventeen factors known or thought to be related to spread of the COVID-19 virus were studied by Poisson regression analysis of confirmed cases and deaths in 883 U.S. counties with a population of 50,000 or more as of May 31, 2020. With little exception, each factor was predictive of incidence and mortality.

 

Most of the correlations are as expected but the lower numbers of cases in counties with a larger percentage of Hispanics in the population is contrary to claims that Hispanics work disproportionately in industries where the virus spread rapidly. 

Similarly, the finding that the cases and deaths are more frequent in counties with higher median incomes may seem counter to the evidence that people with lower incomes are more likely to be exposed to the virus. Again the correlation prevails after controlling for other factors such as unemployment. Recall that one of the early hotspots was Westchester County New York, one of the wealthiest counties in the U.S. It is likely that air travel and business meetings increased risk among more affluent people.

 

The regression equation can be used to identify priority locations for preventive efforts and preparation for medical care caseloads when prevention is unsuccessful. Based on the correlation of cases and deaths to days since stay-at-home orders were issued, the orders reduced the cases about 48 percent  and deaths about 50 percent. The shutdowns probably prevented about 1.4 million cases and 92,000 deaths. The study that claimed the warnings and shutdowns prevented 60 million COVID-19 cases in the U.S. appears to be grossly inflated by a factor of 40. Focusing preventive efforts on the more vulnerable counties may be more effective and less economically damaging than statewide shutdowns.

 

Preprint available at medRxiv (June 26, 2020):

https://doi.org/10.1101/2020.06.25.20139956

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