Newly discovered tick-borne Bourbon virus cured in mice with the experimental flu drug favipiravir | Virus World | Scoop.it

Only a few cases of the newly discovered Bourbon virus have been reported, and two of them ended in death, partly because no specific treatments are available for the tick-borne illness. Now, researchers at Washington University have identified an experimental antiviral drug that cures mice infected with the potentially lethal virus. The drug, favipiravir, is approved in Japan but not the U.S. for treatment of influenza, a related virus. Bourbon virus was first identified in 2014 in a previously healthy middle-aged man in Kansas. The man arrived at the hospital with flu-like symptoms and a history of tick bites. Thinking he had ehrlichiosis, a tick-borne bacterial infection that causes similar symptoms and often affects people in the Midwest, doctors started him on antibiotics. But the man continued to decline, and further testing for ehrlichiosis and every other infection the doctors could think of came up negative. 

Since favipiravir is not approved by the FDA, it is not clear whether doctors in the U.S. would be able to obtain it for their patients. The best protection against Bourbon virus is to avoid tick bites by wearing insect repellent and long pants and sleeves, and doing regular tick checks after outdoor activity, the researchers said.