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BioNTech is taking its mRNA mpox vaccine into the clinic, thanks in part to $90 million from a leading pandemic prevention organization. | BioNTech has partnered up with pandemic prevention organization CEPI to the tune of $90 million to help advance a couple of phase 1 stage mpox vaccines. The funding is part of CEPI's latest 100 Days Mission to help stymie future outbreaks. BioNTech began work on its vaccine, BNT166, as mpox (formerly known as monkeypox) began to spread globally in the summer of 2022. A phase 1/2 trial just got off the ground in August and will test two similar candidates (BNT166a and BNT166c) in patients with or without prior history of mpox infection. “Our work on mpox could broaden the portfolio of vaccines available against this potentially deadly disease, while building our understanding of how mRNA technology performs against orthopoxviruses, a family of viruses that have long afflicted humankind and remain an ongoing threat today,” CEPI CEO Richard Hatchett, M.D., said in the release....
