Genetic Engineering Publications - GEG Tech top picks

In this issue, the authors describe CRISPR-Display (CRISP-Disp), a new approach that deploys RNA-based synthetic devices and lncRNAs to a genomic locus via Cas9-mediated targeting, as both a flexible tool for practical applications and a way to better understand lncRNA function. CRISP-Disp enables a wide range of potential applications, and they demonstrate both orthogonal multiplexing of transcriptional activation at multiple loci and live-cell imaging of a genomic locus using a fluorophore-binding RNA aptamer.

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