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Genetic Engineering Publications - GEG Tech top picks
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CAR T cells, which are now associated with cancer therapy, were previously investigated as a treatment for HIV almost 30 years ago. Now wielding new technology and biological knowledge, Anthony-Gonda et al. report a series of multispecific anti-HIV CARs. These CARs target different portions of the HIV envelope protein and were able to eliminate diverse strains of HIV in vitro, even those that are resistant to potent broadly neutralizing antibodies.