Xenotransplantation has been proposed as a solution to the shortage of suitable human donors for transplantation and pigs are currently favoured as donor animals. However, xenotransplantation may be associated with the transmission of zoonotic microorganisms.The zinc finger nuclease (ZFN) technology was used to reduce the risk of horizontal PERV transmission and to knock out as many as possible proviruses.
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Xenotransplantation has been proposed as a solution to the shortage of suitable human donors for transplantation and pigs are currently favoured as donor animals. However, xenotransplantation may be associated with the transmission of zoonotic microorganisms.The zinc finger nuclease (ZFN) technology was used to reduce the risk of horizontal PERV transmission and to knock out as many as possible proviruses.
www.geg-tech.com/Vectors