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Genetic Engineering Publications - GEG Tech top picks
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In this study, the scientists demonstrate the used CRISPR/Cas9 system to delete single (Ptch1) or multiple genes (Trp53, Pten, Nf1) in the mouse brain, to observe the development of medulloblastoma and glioblastoma, respectively. This method provides a fast and convenient system for validating the emerging wealth of novel candidate tumour suppressor genes and the generation of faithful animal models of human cancer.
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