In this review, the authors give their definition of the concept of synthetic epigenetics and outline the available genome targeting technologies, which are used for locus-specific editing of epigenetic signals. They report early success stories and the lessons they have learned from them, and provide a guide for their application. Finally, they discuss existing limitations of the available technologies and indicate possible areas for further development.
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In this review, the authors give their definition of the concept of synthetic epigenetics and outline the available genome targeting technologies, which are used for locus-specific editing of epigenetic signals. They report early success stories and the lessons they have learned from them, and provide a guide for their application. Finally, they discuss existing limitations of the available technologies and indicate possible areas for further development.
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