In this issue of Molecular Cell, Barrow et al. (2016) use two complementary approaches—one an assessment of a chemical library, and the other a genome-wide CRISPR screen—that both identify bromodomain-containing protein 4 (Brd4) as a therapeutic target for mtDNA diseases affecting complex I.
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In this issue of Molecular Cell, Barrow et al. (2016) use two complementary approaches—one an assessment of a chemical library, and the other a genome-wide CRISPR screen—that both identify bromodomain-containing protein 4 (Brd4) as a therapeutic target for mtDNA diseases affecting complex I.