Genetic Engineering Publications - GEG Tech top picks

Here the authors present two distinct CRISPR-Cas9 genetic screens to identify and characterize functional enhancers in their native context. They show that a genomic CRISPR-Cas9 tiling screen can precisely map functional domains within enhancer elements. Their approach expands the utility of CRISPR-Cas9 to elucidate the functions of the noncoding genome