The authors develop a cross-chiral RNA polymerase, using in vitro evolution starting from a population of random-sequence RNAs. The enzyme’s activity is sufficient to generate full-length copies of its enantiomer through the templated joining of 11 component oligonucleotides.
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The authors develop a cross-chiral RNA polymerase, using in vitro evolution starting from a population of random-sequence RNAs. The enzyme’s activity is sufficient to generate full-length copies of its enantiomer through the templated joining of 11 component oligonucleotides.
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