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For the first time, scientists have created from scratch self-assembling protein filaments built from identical protein subunits that snap together spontaneously to form long, helical, thread-like structures. 
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BigField GEG Tech's insight:
A research team headed by investigators at the Icahn School of Medicine at Mount Sinai (ISMMS) has developed a tool that allows scientists to quickly manipulate levels of two proteins in the same cell. They say the method, dubbed a “dual molecular tuner,” offers an easy way to perform in-depth analyses in mammalian cells in general, and stem cells in particular.
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BigField GEG Tech's insight:
Researchers at the New York University Polytechnic School of Engineering have broken new ground in the development of proteins that form specialized fibers used in medicine and nanotechnology.
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DNA transposition by protein transduction of the piggyBac transposase from lentiviral Gag precursors
BigField GEG Tech's insight:
The smart design of a lentiviral vector that brings a genome editing tool such as a protein. A useful tool for gene transfer!
BigField GEG Tech's curator insight,
December 5, 2013 9:09 AM
The smart design of a lentiviral vector that brings a genome editing tool such as a protein. A useful tool for gene transfer!
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BigField GEG Tech's insight:
Discovering the function of a gene requires cloning a DNA sequence and expressing it. Until now, this was performed on a one-gene-at-a-time basis, causing a bottleneck. Scientists at Rutgers University-New Brunswick in collaboration with Johns Hopkins University and Harvard Medical School have invented a technology to clone thousands of genes simultaneously and create massive libraries of proteins from DNA samples, potentially ushering in a new era of functional genomics.
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BigField GEG Tech's insight:
Chemistry has provided many key tools and techniques to the biological community in the last twenty years. We can now make proteins that Mother Nature never thought of, image unique parts of live cells and even see cells in live animals. In ACS Central Science, three independent research groups from the University of Geneva (UNIGE) and one from the University of Basel (UNIBAS) take these accomplishments a step further, reporting advances in both how proteins are made and how you can see their expression patterns in live animals.
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BigField GEG Tech's insight:
A new technic which allows to observe the vibrations of the proteins, this new tool will surely open new field of investigations!
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This protein-design advance could lead to creatiing materials unlike any in nature and with a range of applications, from diagnostics to nano-electronics.
Published in Science
De novo design of self-assembling helical protein filaments