Genetic Engineering Publications - GEG Tech top picks
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Self-assembling protein filaments created from scratch 

Self-assembling protein filaments created from scratch  | Genetic Engineering Publications - GEG Tech top picks | Scoop.it
For the first time, scientists have created from scratch self-assembling protein filaments built from identical protein subunits that snap together spontaneously to form long, helical, thread-like structures.
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This protein-design advance could lead to creatiing materials unlike any in nature and with a range of applications, from diagnostics to nano-electronics. 

 

Published in Science

 De novo design of self-assembling helical protein filaments

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Structures and mechanisms of CRISPR RNA-guided effector nucleases

Structures and mechanisms of CRISPR RNA-guided effector nucleases | Genetic Engineering Publications - GEG Tech top picks | Scoop.it
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Over the past few years, intensive studies have provided an atomic view of the crRNA-guided target interference mechanisms in different types of CRISPR-Cas systems. Here, the authors review the recent progress toward structural and mechanistic understanding of the diverse crRNP effector nucleases.

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