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Genetic Engineering Publications - GEG Tech top picks
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The author review early experiments using meganucleases, zinc-finger nucleases (ZFN), and transcription-activator like effector nucleases (TALENs) to contract trinucleotide repeats, and discuss the possibility of using CRISPR-Cas nucleases to the same end. Although this is a nascent field, he explores the possibility of designing nucleases and effectively delivering them in the context of gene therapy.
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