Stahlberg et al. describe SiMSen-seq, a barcoding NGS library preparation approach to enable detection of rare variant alleles from as little as 5 ng of input DNA. The method also works for fragmented templates such as cell-free DNA.
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Stahlberg et al. describe SiMSen-seq, a barcoding NGS library preparation approach to enable detection of rare variant alleles from as little as 5 ng of input DNA. The method also works for fragmented templates such as cell-free DNA.