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Genetic Engineering Publications - GEG Tech top picks
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BigField GEG Tech's insight:
This review gives a short primer on gene editing followed by some of the foundational work in gene editing and subsequently a discussion of programmable nucleases leading to a description of Zinc Finger Nuclease, TALENs and CRISPRs. 
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In this review, the authors compare methods for detecting nuclease off-target mutations. They also review methods for profiling genome-wide off-target effects and discuss how to reduce or avoid offtarget mutations.
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