Here, the authors review historical cases of CCR5-edited cell-based therapies, current clinical trials and future benefits and challenges associated with this technology.
This review discusses the current promise and limitations of CCR5 gene editing with engineered nucleases, including factors affecting the efficiency of gene disruption and potential off-target effects.
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Here, the authors review historical cases of CCR5-edited cell-based therapies, current clinical trials and future benefits and challenges associated with this technology.