The authors have developed a method called the mutagenic chain reaction, which is based on the CRISPR/Cas9 genome-editing system for generating autocatalytic mutations, to produce homozygous loss-of-function mutations.
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The authors have developed a method called the mutagenic chain reaction, which is based on the CRISPR/Cas9 genome-editing system for generating autocatalytic mutations, to produce homozygous loss-of-function mutations.
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