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Through extensive studies in the multiple sclerosis model experimental autoimmune encephalomyelitis, we recently demonstrated that regional neural activation induces excess activation of the inflammation amplifier at ... 
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Imaging of immune cell behavior and function in multiple sclerosis ... Pesic 2013 Clinical and Exp Neuroimm http://t.co/1XiBjWYRVd Via Krishan Maggon
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While mental comorbidity is considered common in multiple sclerosis (MS), its impact is poorly defined; methods are needed to support studies of mental comorbidity.
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A Closer Look at Multiple Sclerosis Treatments in 2014: BIIB, NVS, TEVA, SNY ...
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PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Antibody titres at diagnosis and during follow-up of anti-NMDA receptor encephalitis: a retrospective study. By - Nuria Gresa-Arribas PhD, Maarten J Titulaer MD, Abiguei Torrents BS, Esther Aguilar...
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PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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Cunningham Paper Links Autoimmunity with #Neuropsychiatric Symptoms. http://t.co/pqefELUu2B #autoimmunity #mentalhealth #dopamine
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Rheumatology Medical Article: Neuropsychiatric systemic lupus erythematosus: Pathophysiology and the future of treatment (RT @MDLinx: Neuropsychiatric systemic lupus erythematosus: Pathophysiology and the future of treatment: Inte...
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Mechanisms of autoimmunity in the central nervous system: 2013 Clinical and Experimental Neuroimmunology http://t.co/ssl82WabFE
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PubMed comprises more than 23 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
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RT @NatRevNeurol: Recombinant antigen-based assay improves detection of AQP4 antibodies in patients with NMO http://t.co/Nj6jUGuCz1 via @fe…
Gilbert C FAURE's insight:
Conclusions: Serological tests using recombinant AQP4 antigen are significantly more sensitive than tissue-based IIF for detecting AQP4-IgG. Testing should precede immunotherapy; if negative, later-drawn specimens should be tested. AQP4-IgG–seronegative NMO is less frequent than previously reported and is clinically similar to AQP4-IgG–seropositive NMO.
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Glutamic acid decarboxylase (GAD) is the rate-limiting enzyme in the synthesis of gamma-aminobutyric acid (GABA).
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A systematic review examining the clinical efficacy of vitamin D in multiple sclerosis http://t.co/1xPxE4LCJT
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(Cochrane) No hay suficiente evidencia de la eficacia de daclizumab vs placebo en esclerosis múltiple http://t.co/LHI7YwFIzC #NoSinEvidencia Via Krishan Maggon
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Why the FDA didn't approve Genzyme's multiple sclerosis drug, Lemtrada
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Neuromyelitis Optica and NMO-spectrum disorders http://t.co/LzC0wXYDqr
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Immunology: Management of disease modifying treatments in neurological autoimmune diseases of the central nervous ... http://t.co/z0kvs3CmTY
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Autoimmunity, seizures, and status epilepticus. Epilepsia 2013 http://t.co/FcFSrcuJ84
Gilbert C FAURE's curator insight,
December 18, 2013 6:07 AM
already posted in september as pubmed reference see also neurology in this topic http://www.scoop.it/t/autoimmunity?q=neurology
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RT @DrJesusPorta: Anti-JC virus (JCV) antibody prevalence in the JCV Epidemiology in MS (JEMS) trial - Bozic -... http://t.co/xpBG0qgHZh
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RT @GreenJournal: Basis for fluctuations in lymphocyte counts in fingolimod-treated patients with MS
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For centuries after its first description by Galen, the thymus was considered as only a vestigial endocrine organ until the discovery in 1961 by Jacques FAP Miller of its essential role in the development of T (thymo-dependent) lymphocytes.
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RT @BSIHQ: Partners in crime? Mast cells, glia and neuroinflammation. Free article from #immunology http://t.co/Loe3UyyAeX http://t.co/JhUu…;
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RT @GreenJournal: GABAB receptor autoantibody frequency in service serologic evaluation
Gilbert C FAURE's insight:
Conclusion: GABABR autoantibody is a marker of an uncommon but treatable paraneoplastic neurologic disorder, usually occurring in the setting of limbic encephalitis and SCLC.
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Paraneoplastic neurological syndromes Leypoldt Clinical & Experimental Immunology Wiley Online Library http://t.co/C9NgBxJuBn
Gilbert C FAURE's insight:
Paraneoplastic neurological syndromes are immune-mediated erroneous attacks on the central or peripheral nervous systems, or both, directed originally against the tumour itself. They have been known for more than 40 years, but recently the discovery of new subgroups of paraneoplastic encephalitis syndromes with a remarkably good response to immune therapy has ignited new clinical and scientific interest. Knowledge of these subgroups and their associated autoantibodies is important in therapeutic decision-making. However, the abundance of new autoantibodies and syndromes can be confusing. This review paper summarizes current knowledge and new developments in the field of paraneoplastic neurological syndromes, their classification, pathophysiology and treatment.
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a theory focusing on neural activation to explain cell migration into the brain and EAE